More and more adults in the Western world are obese, and the Western high-fat diet might be to blame. These differences were the focus of scientists at the University of California, Riverside UCRwho set out to examine the health consequences of obesity in male and female rodents.
Djurdjica Coss, an associate professor of biomedical sciences in the UCR School of Medicine, led the study, which is now published in the journal Frontiers in Immunology. Coss and colleagues examined the role of the Pregnant modeling Peine hormone estrogen in Prenzlauer Berg show girls fat, as well as the health consequences of being overweight in male versus female rodents.
As the study authors explain, previous studies have suggested that women tend to be lean when they are young but gain weight after menopause because estrogen helps them keep excessive weight at bay. Ovaries are the main source of estradiol Fat Bruhl woman, which is Fat Bruhl woman form of estrogen, in premenopausal females. So, Coss and team wanted to test the protective role of ovary-produced estrogen by removing ovaries in female rodents.
The researchers fed the ovariectomized females a high-fat diet and compared the effects with those of male mice that were fed Fat Bruhl woman same diet. The scientists then examined the male rodents' sperm count, the cyclicity of the estrogen in females, and the markers of metabolic syndrome and inflammation in both male and female rodents.
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Coss summarizes the findings, saying, "We found that the mice proceed to gain weight when fed a high-fat diet, suggesting that ovarian hormones are indeed protective against weight gain. This is a novel finding. She comments on what these results mean for humans, saying, "Mice on [a] high-fat diet develop metabolic Sex en Amberg — a constellation of pathologies that includes type 2 diabetes and insulin insensitivity Fat Bruhl woman similarly to obese humans.
However, the health consequences of carrying excess body weight do not stop.
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On the other hand, "Obese women have difficulty with their menstrual cycles," she adds. Obese female mice show the same, contributing to decreased fertility.
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